Innovative technology that redefines what’s possible
THE ULTRAVECTOR® PLATFORM

The UltraVector® Platform

The key to rapid development and customization

  • Dynamic library of modular components allows for customizable, complex transgene assembly
  • Enables the rational design, construction, and testing of a diverse spectrum of multigenic systems
  • Industrial scale provides multiple options to optimize DNA-based functions
GENOME ENGINEERING

Genome Engineering

Gene delivery providing the desired amount of expression, for the desired time, at the desired location

  • Design of novel and optimization of native DNA and RNA components responsible for regulation of gene expression
  • RheoSwitch Therapeutic System® (RTS®) provides for inducible expression of single or multi-gene systems through an activator ligand
  • Rapid integration of DNA into predictable or targeted genomic locations to achieve stable gene activity over time
PROTEIN ENGINEERING

Protein Engineering

Providing for improved or novel protein biofunctionalities

  • Designing proteins with enhanced stability, solubility, and post-translational modifications
  • Modifying targeting motifs to control protein localization
  • Generating novel enzyme inhibitors and fusion proteins
ANTIBODY DISCOVERY

Antibody Discovery

Allows for antigen targeting using “fully human” monoclonal and polyclonal antibodies

  • mAbLogix™ platform enables production of B-cell libraries for discovery of antibodies
  • Utilizes a cell system in vitro
CELL IDENTIFICATION AND SELECTION

Cell Identification and Purification

Ability to specifically target and work with cells of interest

  • Laser-enabled analysis and processing™ (LEAP™) instrumentation allows for rapid on-plate identification and purification of modified cells
  • Supports advanced stem cell maintenance
  • Facilitates single-cell mRNA analysis
CELL SYSTEM INFORMATICS

Cell System Informatics

Fueling faster design of new gene targets or product pathways

  • Applies proprietary bioinformatics software and database systems for mapping cellular pathways
  • Combines genome-scale modeling with gene expression profiling and proteomics